On intrinsic stress fiber contractile forces in semilunar heart valve interstitial cells using a continuum mixture model
نویسندگان
چکیده
منابع مشابه
From stem cells to viable autologous semilunar heart valve.
BACKGROUND An estimated 275,000 patients undergo heart valve replacement each year. However, existing solutions for valve replacement are complicated by the morbidity associated with lifelong anticoagulation of mechanical valves and the limited durability of bioprostheses. Recent advances in tissue engineering and our understanding of stem cell biology may provide a lifelong solution to these p...
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Stress fibers are band-like features that form with sarcomere-like actin and myosin arrangement between cell regions, resisting myosin contractility. We consider three aspects of stress fiber formation: (1) they form by cytoskeletal actin–myosin interaction when myosin contractile forces are resisted, (2) they propagate in a band-like manner, and (3) they maintain a level of stress and material...
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The clinical, hemodynamic, and pathologic findings in two newborn infants with persistent truncus arteriosus and stenosis of the truncal valve are described. In one case the anatomic features of the basic condition were classic, with a dysplastic semilunar valve which was mainly stenotic and also incompetent, while in the other the truncus arteriosus arose exclusively from the right ventricle a...
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The cells that reside within valve cusps play an integral role in the durability and function of heart valves. There are principally two types of cells found in cusp tissue: the endothelial cells that cover the surface of the cusps and the interstitial cells (ICs) that form a network within the extracellular matrix (ECM) within the body of the cusp. Both cell types exhibit unique functions that...
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This paper studies the effect of the space (distance) between lotteries' outcomes on risk-taking behavior and the shape of estimated utility and probability weighting functions. Previously investigated experimental data shows a significant space effect in the gain domain. As compared to low spaced lotteries, high spaced lotteries are associated with higher risk aversion for high probabilities o...
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ژورنال
عنوان ژورنال: Journal of the Mechanical Behavior of Biomedical Materials
سال: 2016
ISSN: 1751-6161
DOI: 10.1016/j.jmbbm.2015.09.027